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Simple and rapid performance gives optimal user convenience. Excellent accuracy and precision as well as reagent stability.Validated and documented protocols
for automated instruments. Suitable for both large and small laboratories.

COAMATIC® PROTEIN C


A chromogenic kit for the determination of protein C activity in human plasma. No influence of heparin levels up to 3 IU/ml.



Measurement Principle

82 2098 63

Reagents and their stability when opened

Protein C activator
2 vials
3 months
2-8°C
Substrate S-2366
2 vials
3 months
2-8°C

Determinations

Automated methods
up to 180
Microplate method
288
Test tube method
72

Part Number: 82 2098 63

COMATIC® PROTEIN S - FREE


Automated latex ligand immunoassay for the quantitative determination of free Protein S (PS) in human citrated plasma on automated instruments. Two forms of Protein S are present in plasma: free Protein S (40%), and Protein S linked to the complement C4b-binding protein (C4BP) (60%).
Only free Protein S has functional cofactor activity.

Measurement Principle

The presence of free Protein S in the sample is measured as the increase of turbidity produced by the agglutination of two latex reagents.
Purified C4BP adsorbed onto the first latex reagent reacts with a high affinity for free Protein S of patient plasma in the presence of Ca 2+ ions.
The free Protein S adsorbed on the C4BP latex triggers the agglutination reaction with the second latex reagent, which is sensitized with a monoclonal antibody directed against human Protein S. The degree of agglutination will be directly proportional to the free Protein S concentration in the test sample and is
determined by measuring the decrease of the transmitted light at 405 nm caused by the aggregates.

Reagents and their stability when opened

Anti PS MAb Latex
3 vials
1 month
2-8°C
C4BP Buffer
3 vials
exp.date
2-8°C
C4BP Latex
3 vials
1 month
2-8°C

Determinations

Approximately 75 Tests

Part Number: 82 4003 63